Detection of anti-idiotypic antibodies after OKT3 treatment by flow cytometry.

نویسندگان

  • C J Hesse
  • N H Jutte
چکیده

1. Krams SM, Egawa H, Quinn MB, Villanueva JC, GarciaKennedy R, Martinez OM, Apoptosis as a mechanism of cell death in liver allograft rejection, Transplantation 1995; 59: 621. 2. Battersby C, Egerton WS, Balderson G, Kerr JF, Burnett W. Another look at rejection in pig liver allografts. Surgery 1974; 76: 617. 3. Kerr JFR, Searle J, Halliday WJ, et al. The nature of piecemeal necrosis in chronic active hepatitis. Lancet 1979; 2: 827. 4. Patel T, Gores GJ. Apoptosis and hepatobiliary disease. Hepatology 1995; 21: 1725. 5. Wijsman JR, Jonker RR, Keijzer R, Van de Velde CJH, Cornelisse CJ, Van Dierendonck JH. A new method to detect apoptosis in paraffin sections: in situ end.labeling of fragmented DNA. J Histochem Cytochem 1993; 41: 7. 6. Shortman K., Scollay R. Death in the thymus. Nature 1994; 372: 44. 7. Surh CD, Sprent J. T-cell apoptosis detected in situ during positive and negative selection in the thymus. Nature 1994; 372: 100.

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

Comparison of Two Flow Cytometric Methods for Detection of Human Invariant Natural Killer T Cells (iNKT)

Background: Invariant natural killer cells (iNKT) are an important immunoregulatory T cell subset. Currently several flow cytometry-based approaches exist for the identifi-cation of iNKT cells, which rely on using the 6B11 monoclonal antibody or a combina-tion of anti-Vα24 and anti-Vβ11 antibodies. Objective: The aim of this study was to compare the ability of two flow cytometry-based methods f...

متن کامل

Mycophenolate mofetil, together with cyclosporin A, prevents anti-OKT3 antibody response in kidney transplant recipients.

OKT3 monoclonal antibody, a murine IgG2a monoclonal antibody targeting the T cell CD3 antigen, elicits a neutralizing humoral response in 20 to 50% of kidney transplant recipients when the concomitant immunosuppression consists of CsA-Sandimmun (SAND) and azathioprine (AZA). In the present study, we investigated the impact of the newer agents, CsA-Neoral (NEO) and mycophenolate mofetil (MMF) on...

متن کامل

Detection of Human Monocyte-Reactive Alloantibodies by Flow Cytometry After Selective Downmodulation of the Fc Receptor

Monocyte-reactive human alloantibodies may be of importance in situations such as transfusion reactions and bone marrow and kidney transplantation. So far, only complementbinding monocyte-reactive antibodies can be detected with a cytotoxicity assay. No antiglobulin assays are yet available that also detect noncomplement-fixing monocyte-reactive antibodies. The binding of monomeric IgG with hig...

متن کامل

Detection of human monocyte-reactive alloantibodies by flow cytometry after selective downmodulation of the Fc receptor I.

Monocyte-reactive human alloantibodies may be of importance in situations such as transfusion reactions and bone marrow and kidney transplantation. So far, only complement-binding monocyte-reactive antibodies can be detected with a cytotoxicity assay. No antiglobulin assays are yet available that also detect noncomplement-fixing monocyte-reactive antibodies. The binding of monomeric IgG with hi...

متن کامل

A protocol and detailed methodological study on immunogenicity of various experimental vaccines.

This study explores the methodology of various experimental vaccines and their immunogenicity outcome in detail. The idea is to give to the reader a picture of the research methodology behind vaccine development that was used in this research. The novelty of this study bases on the demonstration of the cause and effect of antibodies produced against bacterial and viral proteins (immunogens) as ...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

عنوان ژورنال:
  • Transplantation

دوره 61 1  شماره 

صفحات  -

تاریخ انتشار 1996